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If you’ve spent months, maybe years, trying to treat SIBO naturally with elimination diets, antimicrobials, and round after round of rifaximin, only to watch the symptoms come back every few months, this is for you.
You’re not doing it wrong, you’ve likely just been given the wrong roadmap!
Most SIBO protocols start with the wrong question. They ask, “How do we kill the bacterial overgrowth?” when they should be asking, “Why did the body allow the overgrowth to happen in the first place, and what does it actually need to stop?” That distinction is the difference between treating a symptom and treating the root.
In my functional medicine practice, after working with hundreds of women with chronic, recurring SIBO, I’ve watched the same pattern play out again and again. When we follow the right sequence of healing, not in pieces but in the right order, the body resolves the overgrowth without aggressive intervention 90% of the time.
This blog will walk you through that exact 5-step approach. By the end, you’ll understand why your past protocols may have failed, and what it actually takes to heal and treat SIBO naturally and for good.
SIBO stands for Small Intestinal Bacterial Overgrowth, a condition where bacteria (which normally live in the large intestine) start growing in larger numbers in the small intestine, where they aren’t supposed to thrive.
When this happens, those bacteria start fermenting your food before you can digest and absorb it. The result is gas, bloating, malabsorption, and a cascade of symptoms that can affect everything from your energy to your hormones to your skin.
Research published in the World Journal of Gastroenterology describes SIBO as a heterogeneous syndrome that disrupts nutrient absorption, contributes to systemic inflammation, and creates a downstream cascade affecting everything from immune function to hormone balance.
In a healthy gut, SIBO is prevented through several built-in defense mechanisms. Hydrochloric acid in the stomach kills ingested bacteria. Pancreatic enzymes and bile destroy bacteria that survive the stomach. The migrating motor complex (MMC) sweeps the small intestine clean between meals. Antimicrobial peptides released by gut cells fight infection. The ileocecal valve prevents colonic bacteria from migrating back into the small intestine.
When any of these defense systems breaks down, bacteria can take hold where they shouldn’t. And here’s the critical insight most practitioners miss. SIBO isn’t the disease; it is rather the downstream consequence of one or more of these defense mechanisms failing.
That’s why “killing the bacteria” without identifying which defense system is broken is like bailing water out of a sinking boat without patching the hole.

SIBO presents differently in every person, but the most common symptoms include extreme bloating that gets dramatically worse after meals (often described as looking 6 months pregnant by the end of the day), gas, belching, and flatulence, abdominal pain and cramping, diarrhea, constipation, or alternating between the two, brain fog and mental fatigue, heartburn and reflux, food sensitivities that seem to keep expanding, unintentional weight loss or weight gain, nutrient deficiencies (especially B12, iron, and fat-soluble vitamins), fatigue that doesn’t resolve with sleep, and skin issues like rosacea, eczema, or breakouts.
Many of my clients have lived with these symptoms for years before getting diagnosed. They’ve often been told by conventional doctors that everything looks normal, or that they have IBS and need to manage stress.
If you recognize yourself in this list, you deserve a real answer, not just symptom management.
The most common diagnostic tool is the hydrogen breath test, which measures the gases produced when gut bacteria ferment sugars. There are two types: glucose breath tests and lactulose breath tests.
Glucose breath tests are quickly absorbed in the upper small intestine, making them less prone to false positives but potentially missing SIBO that occurs in the lower small intestine.
Lactulose breath tests travel through the entire small intestine, allowing for the detection of SIBO further down. However, they’re more prone to false positives.
Both tests should measure both hydrogen and methane gases. This matters because hydrogen-dominant SIBO is typically associated with diarrhea, while methane-dominant SIBO (technically called intestinal methanogen overgrowth) is associated with constipation. Treatment differs depending on which gases are dominant.
A recent development worth noting is that hydrogen sulfide testing is finally becoming commercially available. Some women who previously tested negative on standard breath tests actually have hydrogen sulfide overgrowth, which can cause symptoms like rotten-egg smelling gas, severe bloating, and diarrhea.
In my practice, breath tests are one piece of the diagnostic picture, but they’re never the only piece. We also look at comprehensive stool analysis, micronutrient panels, and food sensitivity testing to understand what’s actually happening in the entire digestive ecosystem.
Conventional treatment for SIBO typically follows a predictable path. A round of rifaximin (Xifaxan), often combined with neomycin if methane is dominant. According to a systematic review and meta-analysis, rifaximin eradicated SIBO in approximately 70.8% of cases.
That sounds good on paper. However, here’s what we need to consider and what we aren’t seeing with studies on SIBO in real life.
SIBO recurrence rates after antibiotic treatment are extremely high. A study published in the American Journal of Gastroenterology followed 80 patients who had been successfully treated with rifaximin and found recurrence rates of 12.6% at 3 months, 27.5% at 6 months, and 43.7% at 9 months. Many of my clients have been through 3, 4, or even 5 rounds of rifaximin. Each round costs hundreds of dollars, and the relief is increasingly short-lived.
The reason for this is simple! Antibiotics treat bacteria, and they don’t treat the reason the bacteria overgrew in the first place.
If your stomach acid is still low, your migrating motor complex is still impaired, your drainage pathways are still sluggish, and your immune system is still depleted, the bacteria will simply repopulate the moment you stop the medication. This is why I’ve worked with women who have spent over a decade in the SIBO treatment cycle. Each round brings temporary relief, only to return to symptoms within months.

Here’s where my approach diverges from almost everything you’ve read online about SIBO.
Most “natural” SIBO protocols still operate from the conventional model. Identify the bacteria, kill the bacteria, restore the gut. They just swap rifaximin for berberine, neem, oregano oil, and allicin.
A study published in Global Advances in Health and Medicine found that herbal therapy was at least as effective as rifaximin for the treatment of SIBO. In that study, 46% of patients normalized their lactulose breath tests with herbal therapy compared to 34% with rifaximin (a statistically equivalent result). However, the same problem applies to herbal antimicrobials as it does to pharmaceutical ones. If you skip the foundational work, the bacteria come right back.
There are three commonly recommended natural approaches to SIBO treatment:
The elemental diet is a short-term, all-liquid protocol providing pre-digested nutrients (glucose, amino acids, fatty acids, vitamins, minerals). The theory is that the body absorbs all the nutrients in the upper small intestine, leaving nothing for the bacteria to feed on. Within 2-3 weeks, the bacteria starve.
Research on the elemental diet is impressive. A study published in Digestive Diseases and Sciences found that 80% of patients with SIBO had normalized lactulose breath tests after 14 days on an elemental diet, with an additional 5% normalizing after 21 days.
The challenge is that it’s strict, expensive (around $50/day for the better-tasting Physicians’ Elemental Diet), and difficult to maintain. Most of my clients can’t realistically follow it for 2-3 weeks while running their businesses, raising kids, and trying to stay in their lives.
The low FODMAP diet eliminates fermentable carbohydrates that feed gut bacteria. While it can provide significant symptom relief during treatment, long-term restriction has serious downsides, including reduced microbial diversity, nutrient deficiencies, and increased food fear and sensitivity over time.
I rarely recommend low FODMAP as a long-term protocol. As a short-term symptom management tool during deeper healing, sometimes useful. As a treatment, it’s a Band-Aid on a deeper wound.
Herbal antimicrobials like berberine, neem, oregano oil, allicin, and combination products like Candibactin AR + BR or Dysbiocide + FC-Cidal can be highly effective when used correctly.
The key phrase is “when used correctly.” That means used at the right time in the healing sequence, on a body that’s been prepared to detoxify what they kill, with proper drainage and immune support in place.
Used incorrectly, they can cause severe die-off reactions, increased inflammation, and a worsening of symptoms that drives many women to abandon natural protocols entirely.
This is exactly why my approach looks different. We don’t lead with killing. We lead with rebuilding the terrain. In fact, most of my clients with SIBO never actually make it to this part, because they don’t need it. I’ll explain more about what I mean below!
This is the framework I walk every one of my 1:1 and group coaching clients through. It’s the lab-driven, sequenced approach that addresses SIBO at the root. And it’s the reason most of my clients with SIBO never have to treat it once we get to phase 5 (gut restoration).

Before you can treat SIBO, your body needs the energy to handle treatment. Digestion is the most energy-demanding process in the body. Therefore, the gut takes a lot of energy to heal! This is the step that gets skipped in most SIBO protocols, and it’s the reason so many women feel worse before they feel better, or never feel better at all.
In this phase, we focus on rebuilding the cellular and systemic resources your body needs to do the deeper healing work that follows.
When systemic inflammation is high, antimicrobial treatment dramatically increases that inflammatory load, often triggering severe Herxheimer reactions. We address inflammation FIRST through targeted nutrition, blood sugar stabilization, and reducing inflammatory triggers we identify through testing.
SIBO often develops in women whose immune systems have been depleted by chronic stress, illness, or nutrient deficiencies. Research has identified immunodeficiency syndromes as a recognized risk factor for SIBO, which is why a regulated, well-resourced immune system is essential before any aggressive treatment. After working with hundreds of clients, I’ve consistently seen that women with depleted immune function need foundational support before they can tolerate or benefit from antimicrobial protocols.
ATP (adenosine triphosphate) is the energy currency of your cells. Without adequate ATP, your body simply doesn’t have the resources to detoxify, eliminate pathogens, or repair tissue. We address mitochondrial function with targeted nutrients and other interventions based on lab data.
Through comprehensive lab testing, we identify the specific deficiencies your body needs to be corrected. Common findings in SIBO clients include B12 deficiency (because the bacteria competitively absorb it), iron deficiency, fat-soluble vitamin deficiency (because bacteria deconjugate bile salts and impair fat absorption), and elevated folate levels (because the bacteria themselves produce folate).
This step alone resolves a significant portion of SIBO symptoms in many of my clients, before we’ve ever touched an antimicrobial.
This is where we stop guessing because comprehensive functional medicine testing gives us the actual blueprint of what’s happening in your body, not assumptions based on symptoms.
For my SIBO clients, this typically includes a comprehensive blood chemistry panel (full thyroid, hormones, inflammation markers, fasting glucose, vitamin D), micronutrient testing to identify cellular nutrient status, comprehensive stool analysis to assess the full microbiome (not just SIBO), hormone testing (DUTCH panel when relevant), food sensitivity testing (Mediator Release Test/MRT) to identify foods driving inflammation, heavy metal and toxin testing when indicated, and others based on individual needs to assess bacterial overgrowth, yeast, and metabolic dysfunction.
The data this generates allows us to build a personalized roadmap. This is the difference between giving every SIBO client the same protocol and customizing treatment based on what your body actually needs.
This is one of the most overlooked phases in conventional and even most natural SIBO treatment.
Your body has six primary drainage pathways: the colon, liver/bile, lymphatic system, kidneys, lungs, and skin. When any of these are sluggish or backed up, treatment becomes counterproductive. Pathogens you kill have nowhere to go, so they recirculate, get reabsorbed, and trigger worsening symptoms.
This is why so many women feel terrible during SIBO treatment. It’s not that the treatment is “working.” It’s that their bodies don’t have the capacity to clear what’s being killed.
When drainage pathways are open and flowing, the body becomes capable of handling deeper detoxification work. When they’re closed, even the gentlest antimicrobial protocol can cause significant harm.

The liver is your body’s primary detoxification organ. It processes toxins, hormones, bacterial endotoxins, and metabolic waste, and it does this through two phases of biochemical pathways that require specific nutrients to function.
In SIBO clients, the liver is almost always overburdened. Bacterial endotoxins (specifically lipopolysaccharides, or LPS) constantly leak through compromised gut barriers and put a huge load on liver detoxification. Add environmental toxins, stress hormones, and impaired methylation, and the liver simply can’t keep up.
In this phase, we support the liver with Phase 1 detox nutrients (B vitamins, antioxidants, glutathione precursors), Phase 2 detox nutrients (sulfur amino acids, magnesium, glycine), bile flow support to ensure detoxified compounds actually leave the body, methylation support when MTHFR variants or elevated homocysteine are present, and targeted detox protocols based on what the labs show is most needed (heavy metals, mold, persistent organic pollutants, etc.).
By the time we complete this phase, here’s what most of my clients experience. Their bloating has dramatically reduced, energy has stabilized, and digestion is more predictable. Additionally, many of their original SIBO symptoms have resolved without ever taking a single antimicrobial.
This is the moment that changes how women understand their bodies. They realize the SIBO wasn’t the problem–the terrain was!
Now, we ready to look at the gut directly! Roughly 9 out of 10 of my clients no longer test positive for SIBO at this stage.
The first four phases addressed the underlying root causes. The impaired motility, the low stomach acid, the toxin overload, the depleted immune function, the inflammation, the nutrient deficiencies, the dysbiosis. With those addressed, the bacteria simply lost their reason to overgrow. The body restored its natural defense systems.
This goes against almost everything you’ll read about SIBO online. Most protocols treat antimicrobial treatment as the centerpiece. In my approach, it’s a last-resort step that most clients never need.
For the small percentage who still test positive with labs and symptoms at this phase, we do treat directly, and we do it with confidence, because the body now has the resources to handle it. The herbal antimicrobials work better. The die-off symptoms are minimal, and the results last without relapse.
We focus on cultivating species like Bifidobacteria, Akkermansia, and specific Lactobacillus strains that strengthen the gut lining and reduce inflammation. Research published in Probiotics and Antimicrobial Proteins demonstrated that a multi-strain probiotic combining Saccharomyces boulardii, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus plantarum taken twice daily for 30 days produced a 71.3% reduction in IBS Severity Score in patients with IBS and SIBO, compared to only a 10.6% reduction in patients with IBS without SIBO. The right strains, in the right context, work really well.
Barrier integrity is a main focus in this stage, too. Using key supportive nutrients, we seal and strengthen the intestinal barrier. This prevents the leaky gut that contributed to SIBO in the first place and reverses the immune overactivation that drives autoimmunity.
Foods that previously caused symptoms typically come back into the diet at this stage. The body is no longer reactive because the underlying inflammation and dysbiosis have been resolved.
By the end of this phase, my clients aren’t just symptom-free. They’re resilient. Their bodies can handle a meal out, a vacation, a stressful season, without falling apart!

Even the best functional medicine protocol won’t work if certain foundational lifestyle factors are ignored. The following are non-negotiable in my practice.
Chronic stress directly impairs the migrating motor complex (MMC), which is one of the primary defenses against SIBO. A comprehensive review published in Nature Reviews Gastroenterology and Hepatology confirmed that absence or dysfunction of the MMC is associated with small intestinal bacterial overgrowth, and that the vagus nerve plays a regulatory role in MMC function.
Addressing stress through breathwork, prayer, vagal toning practices, prioritizing rest, and addressing the trauma and overdrive patterns that often drive nervous system dysregulation are a non-negotiable.
Eating too frequently prevents the MMC from doing its job. The MMC is the cleansing wave that sweeps the small intestine clean between meals, but it only activates when the stomach is empty for several hours. I generally recommend 4-5 hours between meals (with no snacking in between) to allow this natural defense to work.
Quality, restorative sleep is essential for immune function, hormone regulation, and tissue repair. We want to address sleep hygiene as a foundational priority, not an afterthought.
Movement supports gut motility, lymphatic flow, and stress regulation. We don’t want to push intense exercise during healing, but we do prioritize daily walking, gentle strength training, and mobility work.
I’ve witnessed incredible health breakthroughs when clients incorporate prayer, scripture, and quiet reflection into their healing protocol. The nervous system regulates. The body remembers it’s safe. The healing accelerates.

In my practice, my 1:1 and group coaching clients work with me for at least 6 months. By the end of that time, most have resolved their SIBO entirely, often without ever directly treating the SIBO itself. Severe or longstanding cases may take longer, especially when there are concurrent issues like autoimmunity, mold toxicity, or significant nervous system dysregulation.
Without addressing the root cause, SIBO rarely resolves and often recurs even after antibiotic treatment. However, when the underlying drivers (low stomach acid, impaired motility, immune dysfunction, inflammation, nutrient deficiencies) are addressed through a comprehensive functional medicine approach, the body’s natural defense mechanisms can restore themselves and clear the overgrowth.
Not necessarily. In fact, I see it to backfire in most cases. While low FODMAP can provide short-term symptom relief, long-term restriction reduces microbial diversity and can worsen gut health over time. In my approach, we use targeted dietary strategies based on lab data, not blanket restriction, to support healing while maintaining nutritional adequacy.
There’s no single “best” herbal antimicrobial. The right choice depends on whether you’re hydrogen-dominant, methane-dominant, or have hydrogen sulfide overgrowth, and on the specific bacterial species involved. Common effective options include berberine, oregano oil, allicin, and combination products like Candibactin AR + BR. But here’s what’s critical: Herbal antimicrobials should never be the first step. They should be used only after foundational work is complete and only when truly needed.
Recurrence is the number one reason women end up in my practice. SIBO comes back when the underlying root cause hasn’t been addressed, usually impaired motility, low stomach acid, chronic stress, or compromised immune function. Each round of antibiotics or antimicrobials treats the bacteria, but if the terrain that allowed the overgrowth still exists, the bacteria simply repopulate. Lasting resolution requires addressing the foundation, not just the bacteria.
Yes, but it requires additional support. Without a gallbladder, bile flow is altered and fat digestion is often impaired, both of which create conditions favorable for SIBO. We address this through targeted bile salt supplementation, digestive enzyme support, and dietary strategies that work with your altered digestive anatomy.
If you’ve been stuck in the SIBO treatment cycle for years, rotating through antimicrobials, restrictive diets, and protocols that work for a few months and then stop, the missing piece isn’t another supplement. It’s the right sequence.
In my 1:1 Private Coaching and Group Coaching programs, I walk every client through the full Abounding 5™ Method. We use comprehensive lab testing to build a personalized roadmap. We address the root cause, not just the symptoms. And we do it in the right order, so your body has the resources it needs at every phase.
I take on 4 new clients per month, combined across both 1:1 and group coaching. This keeps the work white-glove, lab-driven, and personalized to every woman in the program.
If you’re ready to stop guessing and treat SIBO naturally, apply to work together here.

Disclaimer: This blog post is for educational and informational purposes only and is not intended as medical advice. The information provided here should not replace consultation with a qualified healthcare provider. Please consult with your physician or qualified healthcare practitioner before making any changes to your health, diet, supplements, or treatment protocols. The Abounding 5™ Method and the strategies discussed in this post are based on functional medicine principles and clinical experience, but individual results may vary.
"When it comes to balancing our body, healing the gut, reversing autoimmunity, and achieving optimal health—we are a lot like a car that won’t run right. In order to fix the problem once and for all instead of relying on jumper cables, we must get underneath the hood, run the diagnostics, and replace the battery so that it runs good as new."
-Nikki Yelton, RD
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